Wilms’ Tumour (Nephroblastoma)

Responsible for 10% of all childhood malignancies.

Clinical features

• Peak incidence age 2–3
• General symptoms of neoplasia
• Palpable mass (80%)
• Abdominal pain (30%)
• Haematuria (25%)

Classic triad: haematuria + malaise + abdominal mass.

Diagnosis

Urine cytology plus ultrasound or CT/MRI.

Management

Early diagnosis with nephrectomy plus chemotherapy gives a 90% 5-year survival.