Patellofemoral Pain Syndrome

Written 19th February 2020 - Last Update 19th July 2026

Patellofemoral Pain Syndrome

Also known as chondromalacia patellae or anterior knee pain syndrome — the most common overuse injury of the knee.

  • Demographics: runners and cyclists (especially after an increase or change in training); young females most at risk; older adults (50–70) with patellofemoral-joint OA.
  • History:
    • pain behind or around the patella
    • pain descending stairs
    • pain on standing after prolonged sitting (“movie-goer’s knee”).
  • Examination:
    • tenderness around the patellar edges
    • crepitus under the patella on flexion/extension greater than the non-painful side (crepitus without pain has limited significance)
    • pain on moving the patella under compression (Perkins/Clarke-type test — press down on the patella, then glide it medially and laterally).
  • Investigations: none required — clinical diagnosis.
  • Management:
    • reduce the aggravating activity, then slow graded return
    • physiotherapy — quadriceps (and hip/calf) strengthening is the cornerstone
    • correct underlying biomechanical abnormality (foot posture, training load)
    • NSAIDs for short-term pain relief.

Benign condition with a good prognosis.